I started this Blog after being diagnosed with Prostate Cancer in 2010. I thought I was going to die! It was a way of keeping family and friends informed but then became a campaigning tool, helping to make improvements in hospitals nationally. 11 years on, after successful surgery, my PSA is still undetectable. I'm not continuing to Blog about prostate cancer, I'm hoping to leave it in the past, but this blog contains a great archive of information.
The first drug that targets precise genetic mutations in prostate cancer has been shown to be effective in a "milestone" trial by UK scientists.
The study, at the Institute of Cancer Research in London, took place on 49 men with untreatable cancer.
The drug, olaparib, had low overall success, but slowed tumour growth in 88% of patients with specific DNA mutations.
Cancer Research UK said the trial was exciting.
The future of cancer medicine is treating cancers by their mutated DNA rather than what part of the body they are in.
The breast cancer drug Herceptin is already used only in patients with specific mutations. Olaparib targets mutations that change the way DNA is repaired.
The trial results, published in the New England Journal of Medicine, showed the drug worked in 14 out of 16 men with such mutations.
Levels of Prostate Specific Antigen, which is produced by tumours, was more than halved and there were also significant falls in the number of prostate cancer cells detected in the blood and in the size of secondary tumours.
Patients responded to the drug for between six months and nearly a year and a half.
One of the researchers, Dr Joaquin Mateo, told the BBC News website: "It is very promising.
"Those entering the trial had an expected survival of 10 to 12 months and we have many patients on the drug for longer than a year."